Sclerosing mesenteritis, also called mesenteric panniculitis, occurs when the tissue (mesentery) that holds the small intestines in place becomes inflamed and forms scar tissue. Sclerosing mesenteritis is rare, and it's not clear what causes it.
Sclerosing mesenteritis can cause abdominal pain, vomiting, bloating, diarrhea and fever. But some people experience no signs and symptoms and may never need treatment.
In rare cases, scar tissue formed by sclerosing mesenteritis can block food from moving through your digestive tract. In this case, you may need surgery.
Symptoms of sclerosing mesenteritis include pain in your belly, vomiting, bloating, diarrhea and fever. Sometimes people don't have any symptoms.
The cause of sclerosing mesenteritis is not known.
Tests and procedures used to diagnose sclerosing mesenteritis include:
Removing a sample of tissue for testing (biopsy). If you're experiencing sclerosing mesenteritis signs and symptoms, your doctor may recommend a biopsy to rule out other diseases and to make a definitive diagnosis. A biopsy sample may be collected by inserting a long needle through your skin or during surgery.
Before starting treatment, doctors will do a biopsy to confirm the diagnosis and rule out other possibilities, including certain cancers such as lymphoma and carcinoid.
You may be diagnosed with sclerosing mesenteritis while you are receiving care for another condition. If you are not experiencing discomfort from sclerosing mesenteritis, you may not require treatment. Instead, your doctor may recommend periodic imaging tests to monitor your condition.
If you begin to experience signs and symptoms of sclerosing mesenteritis, you may choose to begin treatment.
Medications for sclerosing mesenteritis are intended to control inflammation. Medications may include:
If sclerosing mesenteritis advances to block the flow of food through your digestive system, you may need surgery to remove the blockage.
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