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Home Health Library Symptoms High white blood cell count

High white blood cell count

Learn the causes of this increase in disease-fighting cells in the blood.

Definition

A high white blood cell count is a rise in the number of cells in the blood that fight infections.

What's thought of as high in a white blood cell count varies from one lab to another. This is because labs set their own reference ranges based on the people they serve. Most often, a count of more than 11,000 white blood cells in a microliter of blood is thought to be high for adults.

Causes

A high white blood cell count most often means one of the following has led to a rise in white blood cells:

  • An infection
  • Reaction to a medicine
  • A bone marrow condition
  • An immune system issue
  • Sudden stress such as hard exercise
  • Smoking

Specific causes of a high white blood cell count include:

  • Allergy, mainly bad allergic reactions
  • Asthma
  • Bacterial, viral, fungal or parasitic infections
  • Burns
  • Churg-Strauss syndrome
  • Medicines, such as corticosteroids and epinephrine
  • Hay fever
  • Leukemia
  • Lymphoma
  • Myelofibrosis
  • Polycythemia vera
  • Pregnancy
  • Rheumatoid arthritis
  • Sarcoidosis
  • Smoking
  • Tuberculosis
  • Vasculitis
  • Whooping cough

When to see a doctor

A test a healthcare professional orders to diagnose a condition can show a high white blood cell count. A high white blood cell count rarely is found by chance.

Talk to your healthcare professional about what your results mean. A high white blood cell count plus results from other tests might show the cause of your illness. Or you might need other tests for more information about your condition.

Last Updated: February 19th, 2026